Solitary Increase of 11C-Choline Uptake in an Enchondroma Patient with Biochemical Recurrence of Prostate Cancer

ABSTRACT

We report the case of a 72-yr-old prostate cancer patient with biochemical failure (PSA = 2.8 ng/mL) after radical prostatectomy in whom both bone scintigraphy and 11C-choline PET/CT detected an isolated focal pathological activity in the proximal diaphysis of the left tibia. Surgery was performed and histological analysis revealed enchondroma. The finding is discussed on the basis of the specificity of radiolabeled choline for prostate cancer vs. other tumors or inflammation processes. Particularly, proliferation or concomitant inflammatory processes associated with bone remodeling in enchondroma are discussed and related to 11C-choline uptake.

Keywords: 11C-choline PET/CT; enchondroma; prostate cancer

Citation: Giovacchini G, Ciarmiello A. Solitary Increase of 11C-Choline Uptake in an Enchondroma Patient with Biochemical Recurrence of Prostate Cancer. Journal of Diagnostic Imaging in Therapy. 2016; 3(1): 55-58.

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http://dx.doi.org/10.17229/jdit.2016-0906-024

Copyright: © 2016 Giovacchini G, Ciarmiello A. This is an open-access article distributed under the terms of theCreative Commons Attribution License (CC By 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.

Article History: received 15 August 2016; revised 01 September 2016; accepted 02 September 2016; published online 06 September 2016

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JDIT-2016-0906-024