Nano-Aptamer for Breast Cancer Imaging: Initial Considerations

ABSTRACT

The application of aptamers especially in the use of drug delivery systems (DDSs) has the potential to develop in vivonanoparticles for theranosis (therapy+diagnosis).  With the advent of medical imaging and radiotherapeutics, this area of research developing the next era of radiopharmaceuticals is both attractive and promising.  Overall, nano-radiopharmaceuticals have the potential to solve several problems regarding the in vivo stability of aptamers.  This paper discusses a study in the development and proof-of-concept of nano-aptamers and supporting its use as a nano-radiopharmaceutical for the treatment of breast cancer and other potentially related disease states.

Keywords: radiopharmacy; radiopharmaceuticals; cancer; oncology; drug delivery systems; nano-aptamer

Citation: Santos do Carmo F, Rocha Pinto S, Maria Camões Orlando M, et al. Nano-Aptamer for Breast Cancer Imaging: Initial Considerations. Journal of Diagnostic Imaging in Therapy. 2015; 2(2): 41-49.

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DOI: http://dx.doi.org/10.17229/jdit.2015-0518-018

Copyright: © 2015 Santos do Carmo F, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.

Received: 07 May 2015 | Revised: 15 May 2015 | Accepted: 16 May 2015

Published Online 18 May 2015 http://www.openmedscience.com

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JDIT-2015-0518-018