Basic Premises to Molecular Imaging and Radionuclide Therapy – Part 1

ABSTRACT

This manuscript is a complementary article to an accompanying paper, published in a forthcoming issue, which will give an overview on the central role of chelation in labelling radiocompounds; either for imaging and/or for radionuclide therapy. In order to facilitate a better understanding of the importance of Chelator-Based Imaging & Therapy, we will briefly discuss in this publication – which is partially intended as an introduction to the second paper – which contains the major basic principles of molecular imaging and radionuclide therapy. Although these issues are of interest in the general field of Nuclear Medicine; since the chelation process involves the labelling with radiometals; we aim to highlight examples of this category in this paper which concern this class of nuclides in this particular issue.

Keywords: molecular imaging; radionuclide therapy; radiotracers; chelation; radiometals; radio-halogens; SPECT imaging; PET imaging

Citation: Mansi L, Kitson SL, Cuccurullo V, Ciarmiello A. Basic premises to molecular imaging and radionuclide therapy. Journal of Diagnostic Imaging in Therapy. 2014; 1(1): 137-156.

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DOI: http://dx.doi.org/10.17229/jdit.2014-1125-010

Copyright: © 2014 Mansi L, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.


Received: 04 November 2014 | Revised: 20 November 2014 | Accepted: 21 November 2014

Published Online 25 November 2014 http://www.openmedscience.com

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JDIT-2014-1125-010