Abiraterone and Volumetric Modulated Arc Therapy for Second Recurrence of Node-Positive Prostate Cancer – A Case Report

ABSTRACT

A 50 year old man with prostate cancer was initially treated with radical prostatectomy and pelvic lymph node dissection. He had salvage androgen deprivation therapy (ADT) for persistent measurable prostate specific antigen (PSA). In 2011, the first recurrence was treated with volumetric modulated arc therapy (VMAT). However in 2014, an 11C-choline PET/CT scan indicated a second recurrence with new lesions, in two para-aortal lymph nodes. Abiraterone (Zytiga®) gave a fall of PSA from 2.9 to 0.54 ng/mL over four month period. Following this, a para-aortal lymph node lesion was given VMAT with a boost of 60 Gy. The treatment was well tolerated.

Keywords: Abiraterone; external beam radiotherapy; PET/CT scanning; prostate cancer

Citation: von Eyben FE, Joensuu T, Kangasmaki A, Kairemo K, Kiljunen T. Abiraterone and Volumetric Modulated Arc Therapy for Second Recurrence of Node-Positive Prostate Cancer – A Case Report. Journal of Diagnostic Imaging in Therapy. 2014; 1(1): 73-80.

Crossref logo

DOI: http://dx.doi.org/10.17229/jdit.2014-1028-005

Copyright: © 2014 von Eyben FE, et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cited.


Received: 03 October 2014 | Revised: 28 October 2014 | Accepted: 30 October 2014

Published Online 30 October 2014  http://www.openmedscience.com

Click to download PDF

JDIT-2014-1028-005